Wayne Eskridge published Cirrhosis Could Double Stroke Risk in Voices - our blog 2017-06-09 11:41:42 -0600
Average yearly rate of the attacks doubled in people with the liver disease
From Cornell -- Cirrhosis -- a stiffening of liver tissue that's often tied to excessive drinking of alcohol -- may also raise an older person's odds for a stroke, a new study suggests.
"In a nationally representative sample of elderly patients with vascular risk factors, cirrhosis was associated with an increased risk of stroke, particularly hemorrhagic stroke," wrote a team led by Dr. Neal Parikh, of Weill Cornell Medicine and New York-Presbyterian Hospital in New York City.
Hemorrhagic or "bleeding" stroke comprises about 13 percent of strokes and occurs when a blood vessel ruptures, according to the American Stroke Association. The majority of strokes (87 percent) are ischemic -- meaning they are caused by clots.
In the new study, Parikh's team tracked 2008-2014 data for more than 1.6 million Medicare patients older than 66.
The research showed that while just over 1 percent of people who did not have cirrhosis suffered a stroke during the average year, that number jumped to just over 2 percent for people with the liver disease.
The study couldn't prove that the cirrhosis actually caused any of the strokes. According to the authors, possible explanations for the association between cirrhosis and increased stroke risk include impaired clotting ability. Or, patients' heart risk factors may be exacerbated by cirrhosis and the underlying causes of cirrhosis, such as alcohol abuse, hepatitis C infection and metabolic disease, they said.Read more
Wayne Eskridge published Terminal illness from a doctor's perspective in Caregiver Stories 2017-06-04 18:42:48 -0600
The caregiver journey often ends attending a loved one through the death vigil. It isn't something that we do everyday and for most it is a life affirming or life altering experience. Rarely do we wonder how the professionals that attend to deaths everyday think about the process.
I happened to read a very perceptive piece by Dr Jeremy Topin who wrote in his personal blog, www.jtopin.wordpress.com, about a particular patient. I'll include an excerpt here but recommend reading his entire article.
Mrs. Valentine’s family waits for me in the ICU. The overnight nurse has already filled me in on the evening’s events. The family has come to a unified decision and they have called friends and loved ones from near and far. Their mom has been on the ventilator for six days and continues to get worse. Her pneumonia and kidneys are the most urgent problems, leaving her dependent on a ventilator and dialysis. But underneath the surface, her lung cancer is the real culprit. What started as a time-limited trial to see if her lung infection could get better, had now run its course. The family knows we are no longer helping her to live; we are prolonging her death. This is not what she wanted.
Wayne Eskridge commented on Fatigue, the lifesucker that will stalk you if you become ill 2017-05-10 09:19:21 -0600This discussion deals with how fatty liver patients might deal with fatigue. It would not do to imply that this is the only source of fatigue. For example, with a badly inflamed liver it will increase tumor necrosis factor and interleukin 2. Both of those will make you feel tired and lousy. All medical issues are multifaceted, but the advice in the blog post does apply to life and overlays any other medical issues.
Wayne Eskridge commented on Albumin treatment improves overall survival for decompensated cirrhosis patients 2017-04-23 09:21:53 -0600Given that production of albumin is one of the most important functions of the liver. You would think this would be standard therapy already. Puzzling.
Serum albumin is the main protein of human blood plasma.7 It binds water, cations (such as Ca2+, Na+ and K+), fatty acids, hormones, bilirubin, thyroxine (T4) and pharmaceuticals (including barbiturates): its main function is to regulate the Oncotic pressure of blood. Alpha-fetoprotein (alpha-fetoglobulin) is a fetal plasma protein that binds various cations, fatty acids and bilirubin. Vitamin D-binding protein binds to vitamin D and its metabolites, as well as to fatty acids. The isoelectric point of albumin is 4.9.
Wayne Eskridge commented on Supplements 2017-04-19 21:17:35 -0600Hi Dawn
Beyond the quality control issues of the supplement industry, liver patients need to remember that everything that goes into their body must go to the liver. There are so many chemicals in herbals that we simply don’t know much about that if your liver is sick supplementation is an expensive game of Russian Roulette.
Wayne Eskridge posted about Experts by Experience from Inspire.com - patient stories that inspire on Facebook 2017-04-19 17:36:51 -0600Experts by Experience from Inspire.com - patient stories that inspire
The “Experts by Experience” series are special reports by Inspire developed in cooperation with Stanford University Medical School. Each compilation is comprised of a year’s worth of monthly columns written for Stanford Medicine’s “Scope” medical blog.
In “Experts by Experience 2017,” patients and caregivers affected by such diseases as stomach cancer, bladder cancer, scleroderma, Ehlers-Danlos Syndrome, lipedema, sarcoidosis, share their experiences and insights.
This is what you will find here:
- Non-technical explanation of how your body actually works
- How the liver develops disease over time
- Why fats are a critical source of fuel for your cells
- How the liver manages triglycerides
- How the course of fatty liver disease depends on triglycerides and carbohydrates
- How the kind of dietary fat you use matters
- Information by a liver patient for liver patients
- Information about diet based upon bio-chemistry not fads
We are a nonprofit foundation and we do not represent anyone but the patient. If you are looking for advice on supplements or quick fixes this is not the place for you. We offer extensive information about the body in general, the liver specifically, and we recommend lifestyle strategies that have worked for me specifically and which I believe are valuable for anyone concerned about liver health to be familiar with.
For any non-profit foundation the support of the community is really life and death. We depend upon people who believe that our efforts are of value. We greatly appreciate the support of everyone who helps us. Sponsors are those people and groups who provide help above and beyond just believing in our cause. If you would like to be a sponsor please contact us.
Donations can be made as money or "in kind" and both are very valuable to us. In Kind is any good or service which furthers out goals and serve our community and everything helps.
Legal notice: This site does not provide medical advice
The goal of this website is to share my experiences and information as I seek to use nutrition and a health supportive lifestyle to manage my liver disease. I have to tell you the legal things below because our society is riddled with lawyers.
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Wayne Eskridge published End of life care - Do you care what it is like in Caregiver Stories 2017-02-26 08:56:29 -0700
All of us face the difficult prospect of a parent or loved one suffering from an illness that ultimately leads to death. When that time comes, we will want to ease their physical and emotional pain, respect their wishes, and allow them to die with dignity — the same things we will want for ourselves.
The way that Americans die has changed but, unfortunately, our medical system hasn’t kept up. It was designed at a time when death was often sudden or declines in health were relatively rapid. These days it is often a long and very difficult journey to death. When that time comes, we will want to ease their physical and emotional pain, respect their wishes, and allow them to die with dignity — the same things we will want for ourselves. much more common for people to live longer with multiple chronic conditions, and we have the technology to prolong life as death approaches. End-of-life care is fragmented, intensive, and costly — and patients’ wishes are often lost due to poor communication.
Two serious gaps in health insurance coverage threaten many people facing the end of life. Medicare does not provide coverage for social supports, like breaks for family caregivers, or for the coordination of care. Medicare policy should be changed to include benefits for those diagnosed with advanced illness that provide social supports and care coordination through a defined care team. This kind of coverage would encourage team-based organizations to meet the needs of patients. Medicare should test the integration of its hospice benefit into Medicare Advantage and other demonstrations. Improving efficiency and delivery will help those who are seriously ill get the care they need — and help their caregivers deliver it — without jumping through hurdles and battling a bureaucracy not designed with their circumstances in mind.
Wayne Eskridge posted about A great explanation of fructose, a quiet killer on Facebook 2017-02-22 20:15:48 -0700Great explanation about fructose, a quiet killer you should understand
Fructose’s propensity to cause fatty liver is unique among carbohydrates. The fatty liver directly causes insulin resistance setting in motion the vicious cycle of hyperinsulinemia – insulin resistance. Furthermore, this harmful effect of fructose does not require high blood glucose or blood insulin levels to wreak havoc. Further, this fattening effect, because it acts through fatty liver and insulin resistance, cannot be seen in the short term – only in the long term.
Fructose overconsumption directly produces fatty liver, which in turn directly creates insulin resistance. Fructose is five to ten times more likely than glucose to cause fatty liver. This sets off a vicious cycle. Insulin resistance leads to hyperinsulinemia, to ‘overcome’ this resistance. However, this backfires, as the hyperinsulinemia, made worse by the attendant glucose load, leads to further insulin resistance.
Wayne Eskridge posted about ever_wonder_how_to_kill_a_rat_with_food on Facebook 2017-02-21 08:15:37 -0700Ever wonder how to kill a rat with food
There is a concept of "healthy" saturated fat. Since being saturated refers to a bio-chemistry definition in which all available carbon bonds are used by a hydrogen atom I've wondered what that meant. I had never considered how the research on fibrosis is actually done with animal trials but I was fortunate to be able to recently attend a conference of about 200 of the top liver researchers in the world. The official focus was to update everyone on the progress on the most interesting 20+ drugs inching closer to human trials and possibly a treatment for fibrosis but I was struck by the specifics of how the research is done.
When you want to study how a drug might work against liver disease in a mouse or rat you first have to give it liver disease. How might that be done quickly and cheaply and mimic human disease you might be moved to ask. Well, suppose there are two really good diets you can feed them. It is that simple. There are two main ones that are named the "Western Diet" and the "Fast Food Diet".
I wonder what might be in that food. Would it surprise you to learn they have two main components? Would you bet on lots of saturated fat and sugar? It is that simple. You can give a mouse cirrhosis in weeks by just feeding them what you eat and feed your kids every day.
The information on the bio-chemistry was absolutely fascinating but I was dumbfounded by the little detail of how to create illness that ran through the conference. I'm pondering how to make that more clear to people in general but I offer it here for whatever it may be worth.
Wayne Eskridge posted about The WHO chief cardiologist discussing food and the heart but it applies to your liver as well on Facebook 2017-02-20 12:52:48 -0700WHO chief cardiologist discussing food it applies to your liver as well if health matters join us
For liver patients the discussion about salt in this video is not correct, but the discussions about fats and their effect on health is spot on and backed up by lots of research.
Fatty Liver Foundation organizer
As a liver disease patient my goal is to help others understand, manage, or prevent the disease