NATURE runs clinical trial recruitment, Free Feeding Sugar, Phase 4, genetic response and mortality
TRIAL: A test to determine whether the species will create new organ designs to accommodate chronic over feeding or fail and result in mortality and long term decline. The alternate endpoint, increased intelligence in feeding strategies.
OVERVIEW;
The test subjects all like sugar but dietary advice mostly says give it up. The question, what really happens when they eat excess sugar over time?
OK, but sugar is glucose and it is known that glucose is a fundamental fuel so what is wrong with that? Let's take a walk down bio-chemistry lane. Just a peak so easy peasy. This is really important if one has concerns about livers so don't run away yet.
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Great explanation about fructose, a quiet killer you should understand
Fructose’s propensity to cause fatty liver is unique among carbohydrates. The fatty liver directly causes insulin resistance setting in motion the vicious cycle of hyperinsulinemia – insulin resistance. Furthermore, this harmful effect of fructose does not require high blood glucose or blood insulin levels to wreak havoc. Further, this fattening effect, because it acts through fatty liver and insulin resistance, cannot be seen in the short term – only in the long term.
Fructose, Fatty Liver, and insulin resistance
Fructose overconsumption directly produces fatty liver, which in turn directly creates insulin resistance. Fructose is five to ten times more likely than glucose to cause fatty liver. This sets off a vicious cycle. Insulin resistance leads to hyperinsulinemia, to ‘overcome’ this resistance. However, this backfires, as the hyperinsulinemia, made worse by the attendant glucose load, leads to further insulin resistance.
If fatty liver disease or its cousins concern you, join the Foundation, its free click here
Fructose is a terrible thing to eat but it is everywhere.
Watch this short video to learn about why fructose is bad for you to consume
If fatty liver disease or its cousins concern you, join the Foundation, its free click here
Sugar - Is it bad for my liver?
This discussion focuses on fructose and why it is a real enemy of your liver so think high fructose corn syrup. The little secret is that table sugar is 50% fructose so it is not just calories that we are concerned about.
Fructose, or fruit sugar, is a simple ketonic monosaccharide found in many plants, where it is often bonded to glucose to form the disaccharide sucrose. It is one of the three dietary monosaccharides, along with glucose and galactose, that are absorbed directly into the bloodstream during digestion. Fructose is a very sweet, white, odorless, crystalline solid and is the most water-soluble of all the sugars. Fructose is found in honey, tree and vine fruits, flowers, berries, and most root vegetables. Excessive fructose consumption is a cause of diabetes, obesity, elevated LDL cholesterol and triglycerides, leading to metabolic syndrome, type 2 diabetes and cardiovascular disease, and fatty liver.
