What is NAFLD?

Non-alcoholic fatty liver disease (NAFLD) is one of the types of fatty liver which occurs when fat is deposited (steatosis) in the liver due to causes other than excessive alcohol use. NAFLD is the most common liver disorder in developed countries.

NAFLD is related to diabetes and the metabolic syndrome and may respond to treatments originally developed for other metabolic-resistant states (e.g. diabetes mellitus type 2) such as weight loss, metformin, and thiazolidinediones. Up to 80% of obese people have the disease. Non-alcoholic steatohepatitis (NASH) is the most extreme form of NAFLD, and is regarded as a major cause of cirrhosis of the liver of unknown cause. Most people have a good outcome if the condition is caught in its early stages.

About 25% of people in the United States has NAFLD. With NAFLD, there are usually no symptoms. Some people may develop signs such as tiredness but fatty liver disease is usually a silent killer.

Fatty liver is a reversible condition wherein large vacuoles of triglyceride fat accumulate in liver cells via the process of steatosis (i.e., abnormal retention of lipids within a cell). Despite having multiple causes, fatty liver can be considered a single disease that occurs worldwide in those with excessive alcohol intake and the obese (with or without effects of insulin resistance).

A short John's Hopkin's video with additional information.

What should I look for if I suspect fatty liver? Click this link for more information

Showing 5 reactions

Please check your e-mail for a link to activate your account.
  • Shana Ryan
    commented 2020-02-17 09:00:17 -0700
    Is pink Himalayan salt ok to use if you have NAFLD?
  • Lisa Rappa
    commented 2019-11-10 09:13:07 -0700
    My GP said I have this FL. I tried diets failed, I got lapband surgery failed, I Then found out I have Hashimoto’s Thyroiditis Hypothyroidism making losing weight so very difficult. I gave up. But these past few months with the weight gains I’ve noticed a sensation not pleasant in my right side. I know it’s my liver screaming at me. But 44yrs of weight loss struggle I’m kinda throwing my hands in the air and waiting for something bad to happen.
  • Christopher Harris
    followed this page 2019-01-26 20:03:43 -0700
  • Wayne Eskridge
    commented 2018-06-20 15:39:33 -0600
    There is a lot of information in other pages, this is just an introduction to the subject so take a look at other links in the menu or follow the links from this page.
  • Joe Fernandes
    commented 2018-06-20 14:52:47 -0600
    I wish it were longer,with more on a diet plan with the types,amounts & combinations of foods.Also which foods to avoid to avoid fatty liver disease.

Click for our online community