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We are on the brink of a new kind of medicine

As patients we worry about today and will we be better or worse tomorrow so we barely glimpse the broader medical dynamic that is remaking the very concept of medical care.

There has never been a time like this in human history.  Between 1750 and 1850 medical knowledge doubled.  It doubled again by 1920.  By 2008 it was doubling in about 7.6 years and by 2004 it was about 3.4 years.  It is projected that by 2020 medical knowledge will double in 73 days.  It is inconceivable that our systems can deliver that knowledge to us in the form of treatments at a rapid pace like that but can you imagine what the great leaps might be that may be possible for us as patients.

If you have to be ill, this is a good time to be doing it.  Despite all the frustration, ineffectiveness, lethargy, and downright pigheadedness that can be the patient experience, help is on the way.

This a link to an article a good friend wrote.  I'll tempt you with a sample but it deserves reading in its entirety.


  • There are 114,000 sick patients on the organ transplant list in the U.S., but about 8,000 people die every year waiting for the organs they need, according to data from the United Network for Organ Sharing.
  • Start-ups have invented new organ profusion machines to keep donor organs alive until surgery to reduce organ death and boost the number of organs available for transplant.
  • Scientists are using gene-editing techniques to make it possible to transplant pig kidneys in humans.
  • The Mayo Clinic in Jacksonville is doing stem cell research to develop ways to repair and regenerate damaged organs.
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We join with HTAA to promote liver health in the trucking industry

We are working with the Healthy Trucking Association of America, (HTAA) to help educate and support truckers at risk of liver disease.  It isn't commonly known that truckers have among the highest rates of diabetes and heart disease of any profession which means they also have a high risk of asymptomatic undiagnosed liver disease.  We will be doing a live radio broadcast about liver disease on  INTHECAB  radio at 4:00 PM CST February 6th.  This is internet radio so if you would like to listen click on the link at that time.  If you are a country music fan you may like the station even if you aren't a trucker.



The $35 billion race to treat liver disease

  • The race is on in the pharmaceutical industry to develop drugs to treat a form of fatty liver disease called nonalcoholic steatohepatitis, also known as NASH.
  • Industry experts estimate the global market for these new drugs is $35 billion.
  • The U.S. is spending $5 billion annually in health-care costs related to the disease, which include chemotherapy, transplants, tests and hospitalizations, reports the Center for Disease Analysis.
  • The National Institutes of Health estimates as many as 12 percent of U.S. adults have this disease, or 30 million people.
  • In spite of the large U.S. patient population at risk, the CDC has not addressed the crisis, and there is no FDA-approved treatment available, experts point out.

    Even worse, signs of the disease are asymptomatic, so a person often is not diagnosed with NASH until it advances to a late stage, when cirrhosis begins to ravage the body.By that point the only option is a transplant to avert death. That's because physicians typically do not screen for fatty liver disease as part of the annual physical they give patients when they analyze for other life-threatening conditions, like heart disease, diabetes, breast and colon cancer.

    A fuller discussion can be found here.

    This article was written by Lori Loannou, a friend, who is a senior editor for CNBC. I've summarized a little of it here but recommend the full article to you.

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I can take supplements for liver disease, right?

Superfood  -- Miracle Cure -- doctors don't want you to know -- fix your liver quick

Sound familiar? Have you ever responded to an ad for something to help your liver?  A few of you have as it is a multi-billion dollar business.  Most of us have taken something, mostly on the hope that it might help.  I'd like you to take a minute and examine the question critically of whether or not you can reasonably expect a benefit from products like that.

I want you to click on this picture and study it in a larger size for a minute or two


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A Gift of Hope


I recently attended the 2018 meeting of the American Association for the Study of Liver Disease (AASLD). It is the key liver research association in the US.  It brings together the top researchers in the field with reports on their work.  Since there are no therapies for those of us who have liver disease, this is an important benchmark as we look at the state of research.

I'll discuss this more fully below but the short version is that we will get therapies for liver disease in the next 2 to 5 years.

The message in that, is that it is rational to have hope in the face of a diagnosis of serious disease which currently has no treatment.  I'm reminded of a stanza from a favorite poet, Kipling, in a piece called "IF".

If you can force your heart and nerve and sinew

       to do their turn long after they are gone,

And so hold on when there is nothing in you

      except the will that says to them Hold On.

For so many, holding on is hard to do when faced with the constant strain of chronic illness, but help is on the way. A few observations of the meeting and the state of liver research. This is a little long but it is a big subject, worth your time.


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Someone is killing our doctors, can we help?


The suicide rate for doctors is double that of veterans.  The veteran death toll is a disgrace but you likely haven't heard about the docs.  Can we, as patients, help?

There is an increasing dismay in the liver disease community as more people are shocked to learn that they have cirrhosis. A common question within the community is why wasn't I told? How is it possible that my doctors didn't warn me? As this current of dissatisfaction grows there is a counter current in which medical care is being transformed into a process that commonly satisfies neither doctor nor patient. More dangerously it threatens to kill the soul of medical care and to drive out the best practitioners of the healing art.

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There is a tide in the affairs of men


Hopefully you clicked on the picture to hear the very short quote from Shakespeare.  Sometimes I can't resist a bit of drama.

Since you have an interest in liver disease, I wanted to let you know that we have reached a real milestone in the development of the foundation.  We intend to help change the way liver disease, particularly NASH, is managed and to save the lives of millions who do not know today that they are at risk.

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Do you remember your first time?

There are some benefits to being an advocate.  Sometimes you get to be first. We just finished training and certifying our staff to do FibroScan tests.  As part of that I got to be the first one tested.  Getting to this point has been a long journey, about 9 months, so a birth of sorts though happily a painless one. Everyone shows off baby pictures, here is beauty for anyone who hasn't seen a FibroScan report. This is my new scan. Click on it if you'd like to see the full size view.


Although this note is about our screening project, it is also an opportunity to reinforce our view that with lifestyle changes it can be possible to improve liver health, even for a cirrhosis patient. 

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Moments in Time - Can great things grow from a tiny idea?


In every battle there are moments which mark the end of an era. They portend the beginning of something new and a time when tiny things can sprout and grow to a vast scale. Sometimes analogy man gets loose in my mind and I apologize in advance, but I'm drawn to the stories of things that speak to universal truths. Did you know that the biggest living thing on earth, the giant redwood, grows from one of the smallest tree seeds? The Wellness League may be that tiny seed that just grows.

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The DOOMSDAY CLOCK can we believe the odds are really better for liver therapies?


I recently wrote about my view that for the first time a cirrhosis patient could look forward to real medical therapies.  A few folks felt that I was planting false hopes and that such miracles weren't going to happen.  In light of that, I thought I might provide a broader view of the situation today.

Some of you are old enough to remember that not so long ago Hep C was unknown.  We called the illness non A non B hepatitis. Today we have a cure. A miracle perhaps but also a lesson.

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The DOOMSDAY CLOCK is running backward


For cirrhosis patients there has always been a doomsday clock.  We all know that there are no treatments and only a transplant can save us.  Transplant is on the mind of a lot of us but what do the statistics say?


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Our young adults are dying, do you know why?


OK, get ready. BORING government statistics coming. Sorry, but sometimes it is really important to know what is happening to our children.

Statistics from the CDC, from 1999 to 2016, annual U.S. mortality from cirrhosis increased by 65% from 20,661 to 34,174. Let that sink in for a minute. What if we chart the rate of change of various disease.  Not the number of patients but how it is changing.  Look at this chart for a minute. This shows how fast things are changing and those liver statistics are horrifying.

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Have you been diagnosed with NASH?

If so, you are not alone. This is a link to some patient education materials we are working on as part of our mission to bring the problem of liver disease into the public discussion.

A personal journey with NASH, things you need to know.

Is NOT DYING YET on your bucket list?


The Fatty Liver Foundation exists because I was not willing to be a well behaved member of the parade of misery that liver disease is becoming for our society.  My bucket list includes not dying of liver disease. I do a review from time to time for all the new people. Hopefully it is of some benefit to the old timers, but lets step back and think about our goals.


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Health in the land of unintended consequences


It is said that death and taxes are the only constants but we should include the Law Of Unintended Consequences as a universal truth.  For patients this is particularly true.  We want to be well but every decision carries the potential for things we didn't expect.

How bad is it? It has been projected that today's children will be the first generation in history to have a shorter life span than their parents. Even with the rapid advancement of medicine the society is becoming less well and chronic disease in many forms is epidemic. Even if we live longer, the end of life when we suffer and die slowly and painfully is getting longer for many.  Not the ideal trade off perhaps.


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Your BLISS POINT is being massaged. Do you know who is doing it?


I bet you didn't know you had a Bliss Point, but you do, and it is being manipulated every day by strangers in white coats.

Not to be confused with the G spot, the Bliss Point, is also a source of pleasure but it can become a pathway to disease and death.

The Bliss Point is a concept developed by food researchers.  This is the industrial food industry at work.  The way we perceive most foods is by the combination of salt, sugar, and fat which we interpret as "tastiness".  That perfect combination satisfies our brain and makes us feel good and we "like" that particular food. Well whoop di do, that seems like a good idea, who could object to good tasting food?  Well, none of us really, but how might our response to food be used against us?


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Radio Tour discussing Fatty Liver and NASH

Just a brief programming note.  I spent this morning doing a radio interview tour around the country talking about liver disease.  I was working with Ann Moore, a nurse practitioner specializing in liver disease.  We did interviews with 17 internet only  and live radio stations in an effort to educate the public broadly about liver disease, the need for early detection, and the role of the foundation.

Most of the interviews were live to tape so I don't know when they will air, but if you listen to any of these stations perhaps you will get a chance to hear them.


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Reflections on a small world and silent disease

Last year I wrote about an experience I had while out jogging.  I persist in believing that the doctors know what they are talking about regarding exercise and liver disease so it is a subject that comes up from time to time. For anyone who is interested in the challenge of self image versus father time, here is a link to that earlier item which you might relate to.

winged mercury

I was out on the greenbelt yesterday and there is a nice spot near the river where people like to stop and rest or reflect. I had stopped there and a young woman came running along and also decided to take a break.  Surprisingly, she recognized me as the old guy that she had passed last year and we had a few chuckles about the event.


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Study confirms the value of olive oil for health

First I apologize if this gets too technical.  I usually try to provide information in some hopefully entertaining way but sometimes I have to dig into the details because they are important.

An article in the current New England Journal of Medicine has this article.

Primary Prevention of Cardiovascular Disease with a Mediterranean Diet Supplemented with Extra-Virgin Olive Oil or Nuts

This demands a bit of background since we are a liver disease group and the report is measuring cardiovascular disease.  There are studies of olive oil and liver disease but generally they are not as long or big as this one and many studies lack the rigor. You should also remember that liver disease is the master of co-morbidity.  It is generally not understood that cardiovascular disease is the number one cause of death related to cirrhosis.



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Sugar bad sugary fruit good, got that?

I talk a lot about the problems sugar causes for the body. If you had to pick one reason for why your kid's generation will die younger than yours and be sicker in old age than they should have been you could do worse than pick a soda.  We have a very curious relationship with sugary drinks.  We will happily drink a 16 ounce soda and easily serve it to our kids.  No parent or other apparently rational person will sit down and eat 10 teaspoons of sugar and yet that is a common amount in our soda.

This is a small diversion, but

did you ever wonder how to kill a rat with food?



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